Eiji Kondo,1,2 Osamu Jinnouchi,3 Hiroki Ohnishi,3 Ikuji Kawata,3 Seiichi Nakano,2 Masakazu Goda,1 Yoshiaki Kitamura,1 Koji Abe,1 Hiroshi Hoshikawa,4 Hidehiko Okamoto,5 Noriaki Takeda1 1Department of Otolaryngology, University of Tokushima School of Medicine, Tokushima, Japan; 2Department of Otolaryngology, Kochi National Hospital, Kochi, Japan; 3De
BACKGROUND: We assessed the utility of the dual PI3K/mTOR inhibitor NVP-BEZ235 (BEZ235) as single agent therapy and in combination with conventional chemotherapy for thyroid cancer.METHODOLOGY/PRINCIPAL FINDINGS: Eight cell lines from four types of thyroid cancer (papillary, follicular, anaplastic, medullary) were studied.The cytotoxicity of BEZ235
By combining particle Dishwasher Filter Plate swarm algorithm (PSO) with conventional PID, the hydraulic and temperature control systems of high-temperature and high-pressure triaxial testing machine was analyzed and studied, the mathematical models of hydraulic system and temperature control system were established.The performance of the control s
Toys Dental implants sometimes need bone augmentation to recreate an adequate bone height and volume.Numerous bone augmentation techniques have been described, and, currently, the most commonly used bone graft procedure is xenografts with deproteinized bovine bone mineral (DBBM).The addition of platelet-rich fibrin (PRF) to DBBM has already shown b
Predicting the volume of corrosion products (CP) and their distribution in the steel rebar periphery will play an essential role in estimating the expansion stresses and, consequently, the behaviour of concrete in extreme environmental circumstances.In this respect, using the outcomes of performed laboratory studies, an attempt has been made to eva